kinase 1 (Cell Signaling Technology Inc)

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Cell Signaling Technology Inc kinase 1
Kinase 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 194 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kinase+1+ask1/Phospho-ASK1+(Thr845)+Antibody/10__1016_slash_s1875___5364_ascii40_24_ascii41_60578___9-29-29-38
Average 95 stars, based on 194 article reviews

kinase 1 - by Bioz Stars, 2026-10

95/100 stars

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Concentration Assay:

Article Title: TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells
Article Snippet: .. The source and concentration of antibodies used in the immunoblot analysis were as follows: TRAF3IP2 (1 μg/ml, IMG-563, Novus Biologicals, Littleton, CO), tubulin (1:1,000, no. 2144, Cell Signaling Technology, Beverly, MA), phospho-JNK (Thr 183 /Tyr 185 , 1:1,000, no. 9251, Cell Signaling Technology), JNK (1:1,000, no. 9252, Cell Signaling Technology), phospho-c-Jun (Ser 63 , 1:1,000, no. 9261, Cell Signaling Technology), c-Jun (1:1,000, no. 9165, Cell Signaling Technology), apoptosis signal-regulating kinase 1 (ASK1) (1:1,000, no. 8622, Cell Signaling Technology), Akt (1 μg/ml, no. 9272, Cell Signaling Technology), phospho-IKKβ (1:1,000, no. 2697, Cell Signaling Technology), IKKβ (1:1,000, no. 2370, Cell Signaling Technology), phospho-p65 (1:1,000, no. 3033, Cell Signaling Technology), p65 (1:1,000, no. 3034, Cell Signaling Technology), ECE1 (1 μg/ml, ab71829, Abcam, Cambridge, MA), ICAM-1 (1:400, sc-8439, Santa Cruz Biotechnology), VCAM-1 (1:200, sc-8304, Santa Cruz Biotechnology), and cleaved caspase-3 (1 μg/ml, no. 9664, Cell Signaling Technology). .. ET-1, IL-1β, and TNF-α levels in equal amounts of culture supernatants were quantified by ELISA using the following kits: ET-1 (Human Endothelin-1 QuantiGlo ELISA kit, QEST00B, sensitivity: 0.102 pg/ml, R&D Systems, Minneapolis, MN), IL-1β (Human IL-1 beta/IL-1F2 Quantikine HS ELISA Kit, HSLB00D, sensitivity: 0.063 pg/ml, R&D Systems), and TNF-α (Human TNF-alpha Quantikine ELISA Kit, DTA00C, sensitivity: 5.5 pg/ml, R&D Systems).

Western Blot:

Biomarker Discovery:

Article Title: Apoptosis signal-regulating kinase 1 (ASK1) as a therapeutic target for neurological diseases.
Article Snippet: .. Submit your article to this journal View related articles View Crossmark data Information Classification: General Publisher: Taylor & Francis & Informa UK Limited, trading as Taylor & Francis Group Journal: Expert Opinion on Therapeutic Targets DOI: 10.1080/14728222.2020.1821648 Apoptosis signal-regulating kinase 1 (ASK1) as a therapeutic target for neurological diseases Satoshi Takenaka1, Takao Fujisawa1 and Hidenori Ichijo1 1The Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan Corresponding author: Hidenori Ichijo: The Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan ichijo@mol.f.u-tokyo.ac.jp Tel. (+81) 3-5841-4858; Fax. (+81) 3-5841-4798 Keywords: Apoptosis signal-regulating kinase 1, ASK1, Amyotrophic lateral sclerosis, Neurological diseases, Multiple sclerosis AC CE PT ED MA NU CR IP T Information Classification: General ..

other:

Article Title: Nobiletin prevents cadmium-induced neuronal apoptosis by inhibiting reactive oxygen species and modulating JNK/ERK1/2 and Akt/mTOR networks in rats.
Article Snippet: Objectives: Cadmium (Cd), an extremely noxious environmental pollutant is known to induce oxidative stress leading to neurodegenerative diseases.. Nobiletin, a citrus flavonoid is reported to possess various pharmacological properties.. This study investigates the effects of nobiletin over Cd-induced neuronal apoptosis in rodent experimental model. Methods: To separate group of male Sprague Dawley rats, Cd (2 mL/kg/day) was subcutaneously injected for one month which results in a dose level of 1 mg/kg Cd.

Incubation:

Article Title: Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis.
Article Snippet: .. 7, Issue 17 http://www.thno.org 4194 size-separated by 10% SDS-PAGE, transferred to PVDF membranes, and blocked with 5% non-fat dry milk before being incubated with primary antibodies: mitofusin-1 (MFN1) (Proteintech, Chicago, IL), dynamic-related protein-1 (DRP1) (Proteintech), fission-1 (FIS1) (Santa Cruz Biotechnology, Santa Cruz, CA), apoptosis signal-regulating kinase 1 (ASK1) (Cell Signaling Technology, Danvers, MA), phosphorated-c-Jun N-terminal Kinase (p-JNK) (Cell Signaling Technology), phosphorated-c-Jun (p-c-Jun) (Cell Signaling Technology), apoptosis protease activating factor-1 (Apaf-1) (Proteintech), cytochrome c (Cyt c) (Cell Signaling Technology), caspase 3 (Cell Signaling Technology), cleaved caspase 3 (Cell Signaling Technology), PARP (Cell Signaling Technology), cleaved PARP (Cell Signaling Technology), apoptosis-inducing factor (AIF) (Cell Signaling Technology), and endonuclease G (EndoG) (Cell Signaling Technology). .. Secondary antibodies were anti–mouse IgG and anti-rabbit IgG (1:5000 dilutions, Cell Signaling Technology).

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